Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

336

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P63138 (Created: 2004-09-13 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

GBRB2_RAT

Protein Name

Gamma-aminobutyric acid receptor subunit beta-2

Gene

Gabrb2

Organism Scientific

Rattus norvegicus

Organism Common

Rat

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Rattus

Protein Length [aa]

474

Protein Mass [Da]

54633

Features

TypeDescriptionStatusStartEnd
signal peptide      by similarity   1   25
chain   Gamma-aminobutyric acid receptor subunit beta-2      26   474
disulfide bond      by similarity   160   174
transmembrane region      probable   245   266
transmembrane region      probable   270   292
transmembrane region      probable   304   326
transmembrane region      probable   452   473
topological domain   Extracellular   probable   26   244
topological domain   Cytoplasmic   probable   327   451
modified residue   Phosphotyrosine   by similarity   396   396
modified residue   Phosphotyrosine   by similarity   403   403
glycosylation site   N-linked (GlcNAc...)   potential   32   32
glycosylation site   N-linked (GlcNAc...)   potential   104   104
glycosylation site   N-linked (GlcNAc...)   potential   173   173
cross-link   Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)   by similarity   45   45

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MWRVRKRGYFGIWSFPLIIAAVCAQ

Sequence

MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIR
LRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNV
IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY
GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVT
GVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTY
MPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAANANN
EKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASS
IQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAID
RWSRIFFPVVFSFFNIVYWLYYVN

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website