Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

343

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P97785 (Created: 1997-11-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

GFRA1_MOUSE

Protein Name

GDNF family receptor alpha-1

Gene

Gfra1

Organism Scientific

Mus musculus

Organism Common

Mouse

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Glires
                    Rodentia
                      Sciurognathi
                        Muroidea
                          Muridae
                            Murinae
                              Mus

Protein Length [aa]

468

Protein Mass [Da]

51782

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   24
chain   GDNF family receptor alpha-1      25   430
disulfide bond      by similarity   29   87
disulfide bond      by similarity   36   42
disulfide bond      by similarity   52   72
disulfide bond      by similarity   89   99
disulfide bond      by similarity   154   214
disulfide bond      by similarity   161   167
disulfide bond      by similarity   178   192
disulfide bond      by similarity   187   233
disulfide bond      by similarity   216   221
disulfide bond      by similarity   243   313
disulfide bond      by similarity   250   256
disulfide bond      by similarity   267   285
disulfide bond      by similarity   277   337
disulfide bond      by similarity   315   325
glycosylation site   N-linked (GlcNAc...)   potential   59   59
glycosylation site   N-linked (GlcNAc...)   potential   347   347
glycosylation site   N-linked (GlcNAc...)   potential   406   406
repeat   1      25   113
repeat   2      150   238
repeat   3      239   342
propeptide   Removed in mature form   potential   431   468
compositionally biased region   Thr-rich      362   369
lipid moiety-binding region   GPI-anchor amidated serine   potential   430   430

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MFLATLYFVLPLLDLLMSAEVSGG

Sequence

MFLATLYFVLPLLDLLMSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLR
QCVAGKETNFSLTSGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCL
RIYWSMYQSLQGNDLLEDSPYEPVNSRLSDIFRAVPFISDVFQQVEHISK
GNNCLDAAKACNLDDTCKKYRSAYITPCTTSMSNEVCNRRKCHKALRQFF
DKVPAKHSYGMLFCSCRDVACTERRRQTIVPVCSYEERERPNCLNLQDSC
KTNYICRSRLADFFTNCQPESRSVSNCLKENYADCLLAYSGLIGTVMTPN
YIDSSSLSVAPWCDCSNSGNDLEDCLKFLNFFKDNTCLKNAIQAFGNGSD
VTMWQPAPPVQTTTAMTTTAFRIKNKPLGPAGSENEIPTHVLPPCANLQA
QKLKSNVSGSTHLCLSDNDYGKDGLAGASSHITTKSMAAPPSCGLSSLPV
MVFTALAALLSVSLAETS

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website