Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

356

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P47871 (Created: 1996-02-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

GLR_HUMAN

Protein Name

Glucagon receptor

Gene

GCGR

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

477

Protein Mass [Da]

54009

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   25
chain   Glucagon receptor      26   477
transmembrane region   1   potential   143   166
transmembrane region   2   potential   174   193
transmembrane region   3   potential   226   249
transmembrane region   4   potential   264   285
transmembrane region   5   potential   304   326
transmembrane region   6   potential   351   369
transmembrane region   7   potential   382   404
topological domain   Extracellular   potential   26   142
topological domain   Cytoplasmic   potential   167   173
topological domain   Extracellular   potential   194   225
topological domain   Cytoplasmic   potential   250   263
topological domain   Extracellular   potential   286   303
topological domain   Cytoplasmic   potential   327   350
topological domain   Extracellular   potential   370   381
topological domain   Cytoplasmic   potential   405   477
glycosylation site   N-linked (GlcNAc...)   potential   46   46
glycosylation site   N-linked (GlcNAc...)   potential   59   59
glycosylation site   N-linked (GlcNAc...)   potential   74   74
glycosylation site   N-linked (GlcNAc...)   potential   78   78
sequence variant   (in dbSNP:rs1801483)      0   0
sequence variant   (in dbSNP:rs5385)      0   0
sequence variant   (in dbSNP:rs5387)      0   0

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MPPCQPQRPLLLLLLLLACQPQVPS

Sequence

MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLL
PPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRC
GPDGQWVRGPRGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYS
LSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRT
RYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLH
NLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKS
TLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLY
CFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGPPSKELQF
GRGGGSQDSSAETPLAGGLPRLAESPF

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website