Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

373

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P10144 (Created: 1989-07-01 Updated: 2009-01-20)

UniProtKB/Swiss-Prot Entry Name

GRAB_HUMAN

Protein Name

Granzyme B

Gene

GZMB

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

247

Protein Mass [Da]

27688

Features

TypeDescriptionStatusStartEnd
signal peptide         1   18
chain   Granzyme B      21   247
disulfide bond         49   65
disulfide bond         142   209
disulfide bond         173   188
domain   Peptidase S1      21   245
glycosylation site   N-linked (GlcNAc...)      71   71
glycosylation site   N-linked (GlcNAc...)   potential   104   104
sequence variant   (in dbSNP:rs2236338)      0   0
sequence variant   (in dbSNP:rs8192917)      0   0
sequence variant   (in dbSNP:rs11539752)      0   0
strand         35   41
strand         46   55
strand         58   61
strand         68   75
strand         87   96
strand         110   116
strand         141   148
strand         150   154
strand         161   166
strand         186   189
strand         205   209
strand         212   220
strand         228   232
helix         63   65
helix         170   176
helix         233   236
helix         237   245
active site   Charge relay system      64   64
active site   Charge relay system      108   108
active site   Charge relay system      203   203
propeptide   Activation peptide      19   20
turn         102   104
turn         177   180
turn         183   185

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MQPILLLLAFLLLPRADA

Sequence

MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCG
GFLIQDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAY
NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQT
APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK
GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website