Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

376

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q13002 (Created: 1997-11-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

GRIK2_HUMAN

Protein Name

Glutamate receptor, ionotropic kainate 2

Gene

GRIK2

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

908

Protein Mass [Da]

102583

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   31
chain   Glutamate receptor, ionotropic kainate 2      32   908
transmembrane region      potential   562   582
transmembrane region      potential   636   656
transmembrane region      potential   820   840
topological domain   Extracellular   potential   32   561
topological domain   Cytoplasmic   potential   583   635
topological domain   Extracellular   potential   657   819
topological domain   Cytoplasmic   potential   841   908
region of interest   Glutamate binding   by similarity   516   518
region of interest   Glutamate binding   by similarity   689   690
glycosylation site   N-linked (GlcNAc...)   potential   67   67
glycosylation site   N-linked (GlcNAc...)   potential   73   73
glycosylation site   N-linked (GlcNAc...)   potential   275   275
glycosylation site   N-linked (GlcNAc...)   potential   378   378
glycosylation site   N-linked (GlcNAc...)   potential   412   412
glycosylation site   N-linked (GlcNAc...)   potential   423   423
glycosylation site   N-linked (GlcNAc...)   potential   430   430
glycosylation site   N-linked (GlcNAc...)   potential   546   546
sequence variant   (in dbSNP:rs2235076)      0   0
sequence variant   (in RNA edited version)      0   0
sequence variant   (in a breast cancer sample; somatic mutation)      0   0
sequence variant   (in RNA edited version)      0   0
sequence variant   (in RNA edited version)      0   0
sequence variant   (in dbSNP:rs3213608)      0   0
splice variant   (in isoform 2)      0   0
splice variant   (in isoform 5)      0   0
splice variant   (in isoform 4)      547   622
splice variant   (in isoform 3)      585   908
binding site   Glutamate   by similarity   523   523
binding site   Glutamate   by similarity   738   738

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKIIFPILSNPVFRRTVKLLLCLLWIGYSQG

Sequence

MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPM
GAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLS
LGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLY
PDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLK
IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTE
YYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMER
LQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRH
KPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLE
KIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSD
KPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDANGQWNG
MVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNP
GVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSD
VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISS
YTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKIS
TYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNC
NLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWR
GNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA
QLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRR
LPGKETMA

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website