Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

410

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P20959 (Created: 1991-02-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

IBP3_BOVIN

Protein Name

Insulin-like growth factor-binding protein 3

Gene

IGFBP3

Organism Scientific

Bos taurus

Organism Common

Bovine

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Laurasiatheria
                  Cetartiodactyla
                    Ruminantia
                      Pecora
                        Bovidae
                          Bovinae
                            Bos

Protein Length [aa]

291

Protein Mass [Da]

31570

Features

TypeDescriptionStatusStartEnd
signal peptide         1   27
chain   Insulin-like growth factor-binding protein 3      28   291
disulfide bond      by similarity   213   240
disulfide bond      by similarity   251   262
disulfide bond      by similarity   264   285
domain   IGFBP N-terminal      36   119
domain   Thyroglobulin type-1      210   285
region of interest   IGF-binding   potential   28   134
glycosylation site   N-linked (GlcNAc...)   potential   118   118
glycosylation site   N-linked (GlcNAc...)   potential   136   136
glycosylation site   N-linked (GlcNAc...)   potential   199   199
compositionally biased region   Ser/Thr-rich      138   161
compositionally biased region   Ser/Thr-rich      192   208

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MLRARPALWAAALTALTLLRGPPAARA

Sequence

MLRARPALWAAALTALTLLRGPPAARAGAGTMGAGPVVRCEPCDARAVAQ
CAPPPPSPPCAELVREPGCGCCLTCALREGQPCGVYTERCGSGLRCQPPP
GDPRPLQALLDGRGLCANASAVGRLRPYLLPSASGNGSESEEDHSMGSTE
NQAGPSTHRVPVSKFHPIHTKMDVIKKGHAKDSQRYKVDYESQSTDTQNF
SSESKRETEYGPCRREMEDTLNHLKFLNMLSPRGIHIPNCDKKGFYKKKQ
CRPSKGRKRGFCWCVDKYGQPLPGFDVKGKGDVHCYSMESK

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website