Signal Peptide Database

Signal Peptide Database - Mammalia

Entry Details

422

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q969P0 (Created: 2006-03-07 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

IGSF8_HUMAN

Protein Name

Immunoglobulin superfamily member 8

Gene

IGSF8

Organism Scientific

Homo sapiens

Organism Common

Human

Lineage

Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo

Protein Length [aa]

613

Protein Mass [Da]

65034

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   27
chain   Immunoglobulin superfamily member 8      28   613
disulfide bond      by similarity   49   127
disulfide bond      by similarity   186   270
disulfide bond      by similarity   326   406
disulfide bond      by similarity   462   544
transmembrane region      potential   580   600
topological domain   Extracellular   potential   28   579
topological domain   Cytoplasmic   potential   601   613
domain   Ig-like C2-type 1      28   149
domain   Ig-like C2-type 2      162   286
domain   Ig-like C2-type 3      303   424
domain   Ig-like C2-type 4      431   560
modified residue   Phosphoserine   by similarity   12   12
glycosylation site   N-linked (GlcNAc...)   potential   50   50
glycosylation site   N-linked (GlcNAc...)   potential   327   327
splice variant   (in isoform 2)      0   0
splice variant   (in isoform 2)      1   241
splice variant   (in isoform 3)      475   561
short sequence motif   EWI motif      274   276

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MGALRPTLLPPSLPLLLLLMLGMGCWA

Sequence

MGALRPTLLPPSLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCN
VTGYEGPAQQNFEWFLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEV
QVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLP
DVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAV
SFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGT
DRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQT
LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPA
GAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGD
AGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGG
TVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGV
GQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWV
QHADYSWYQAGSARSGPVTVYPYMHALDTLFVPLLVGTGVALVTGATVLG
TITCCFMKRLRKR

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website