Signal Peptide Website


Signal Peptide Database - Mammalia

 Entry Details
ID   423
Source Database   UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number   P22301    (Created: 1991-08-01 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name   IL10_HUMAN
Protein Name   Interleukin-10
Gene   IL10
Organism Scientific   Homo sapiens
Organism Common   Human
Lineage   Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo
Protein Length [aa]   178
Protein Mass [Da]   20517
Features  
TypeDescriptionStatusStartEnd
signal peptide         1   18
chain   Interleukin-10      19   178
disulfide bond         30   126
disulfide bond         80   132
glycosylation site   N-linked (GlcNAc...)   potential   134   134
sequence variant   (in CD; decreases secretion thereby reducing the anti-inflammatory effect)      0   0
helix         37   58
helix         68   75
helix         79   92
helix         95   98
helix         103   105
helix         106   125
helix         131   133
helix         137   149
helix         151   159
helix         161   176
turn         29   36
SP Length   18
 ----+----1----+----2----+----3----+----4----+----5
Signal Peptide MHSSALLCCLVLLTGVRA
Sequence MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSR
VKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAEN
QDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQ
EKGIYKAMSEFDIFINYIEAYMTMKIRN
Original MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSR
VKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAEN
QDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQ
EKGIYKAMSEFDIFINYIEAYMTMKIRN
 ----+----1----+----2----+----3----+----4----+----5
Hydropathies  
 
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