Signal Peptide Database - Mammalia

 Entry Details
ID   5
Source Database   UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number   P30483    (Created: 1993-04-01 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name   1B45_HUMAN
Protein Name   HLA class I histocompatibility antigen, B-45 alpha chain
Gene   HLA-B
Organism Scientific   Homo sapiens
Organism Common   Human
Lineage   Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo
Protein Length [aa]   362
Protein Mass [Da]   40414
Features  
TypeDescriptionStatusStartEnd
signal peptide         1   24
chain   HLA class I histocompatibility antigen, B-45 alpha chain      25   362
disulfide bond      by similarity   125   188
disulfide bond      by similarity   227   283
transmembrane region      potential   310   333
topological domain   Extracellular   potential   25   309
topological domain   Cytoplasmic   potential   334   362
domain   Ig-like C1-type      209   295
region of interest   Alpha-1      25   114
region of interest   Alpha-2      115   206
region of interest   Alpha-3      207   298
region of interest   Connecting peptide      299   309
glycosylation site   N-linked (GlcNAc...)   by similarity   110   110
sequence variant   (in allele B*4503)      0   0
sequence variant   (in allele B*4504)      0   0
SP Length   24
 ----+----1----+----2----+----3----+----4----+----5
Signal Peptide MRVTAPRTVLLLLSAALALTETWA
Sequence MRVTAPRTVLLLLSAALALTETWAGSHSMRYFHTAMSRPGRGEPRFITVG
YVDDTLFVRFDSDATSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRE
SLRNLRGYY
NQSEAGSHTWQRMYGCDLGPDGRLLRGYNQLAYDGKDYIAL
NEDLSSWTAADTAAQITQRKWEAARVAEQDRAYLEGLCVESLRRYLENGK
ETLQRA
DPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQ
DTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW
EP
SSQSTIPIV
GIVAGLAVLAVVVIGAVVATVMCRRKSSGGKGGSYSQAASS
DSAQGSDVSLTA
Original MRVTAPRTVLLLLSAALALTETWAGSHSMRYFHTAMSRPGRGEPRFITVG
YVDDTLFVRFDSDATSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRE
SLRNLRGYYNQSEAGSHTWQRMYGCDLGPDGRLLRGYNQLAYDGKDYIAL
NEDLSSWTAADTAAQITQRKWEAARVAEQDRAYLEGLCVESLRRYLENGK
ETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQ
DTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP
SSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGKGGSYSQAASS
DSAQGSDVSLTA
 ----+----1----+----2----+----3----+----4----+----5
Hydropathies  
 

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