Signal Peptide Database - Mammalia

 Entry Details
ID   6
Source Database   UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number   Q9TNN7    (Created: 2003-08-22 Updated: 2009-01-20)
UniProtKB/Swiss-Prot Entry Name   1C05_HUMAN
Protein Name   HLA class I histocompatibility antigen, Cw-5 alpha chain
Gene   HLA-C
Organism Scientific   Homo sapiens
Organism Common   Human
Lineage   Eukaryota
  Metazoa
    Chordata
      Craniata
        Vertebrata
          Euteleostomi
            Mammalia
              Eutheria
                Euarchontoglires
                  Primates
                    Haplorrhini
                      Catarrhini
                        Hominidae
                          Homo
Protein Length [aa]   366
Protein Mass [Da]   40912
Features  
TypeDescriptionStatusStartEnd
signal peptide         1   24
chain   HLA class I histocompatibility antigen, Cw-5 alpha chain      25   366
disulfide bond      by similarity   125   188
disulfide bond      by similarity   227   283
transmembrane region      potential   309   333
topological domain   Extracellular   potential   25   308
topological domain   Cytoplasmic   potential   334   366
domain   Ig-like C1-type      209   297
region of interest   Alpha-1      25   114
region of interest   Alpha-2      115   206
region of interest   Alpha-3      207   298
region of interest   Connecting peptide      299   308
glycosylation site   N-linked (GlcNAc...)   by similarity   110   110
sequence variant   (in allele Cw*0504)      0   0
sequence variant   (in allele Cw*0504)      0   0
sequence variant   (in allele Cw*0502)      0   0
sequence variant   (in allele Cw*0503)      0   0
sequence variant   (in allele Cw*0503)      0   0
sequence variant   (in allele Cw*0503)      0   0
SP Length   24
 ----+----1----+----2----+----3----+----4----+----5
Signal Peptide MRVMAPRTLILLLSGALALTETWA
Sequence MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPGRGEPRFIAVG
YVDDTQFVQFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRV
NLRKLRGYY
NQSEAGSHTLQRMYGCDLGPDGRLLRGYNQFAYDGKDYIAL
NEDLRSWTAADKAAQITQRKWEAAREAEQRRAYLEGTCVEWLRRYLENGK
KTLQRA
EHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQ
DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRW
GP
SSQPTIPI
VGIVAGLAVLAVLAVLGAVMAVVMCRRKSSGGKGGSCSQAAS
SNSAQGSDESLIACKA
Original MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPGRGEPRFIAVG
YVDDTQFVQFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRV
NLRKLRGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYNQFAYDGKDYIAL
NEDLRSWTAADKAAQITQRKWEAAREAEQRRAYLEGTCVEWLRRYLENGK
KTLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQ
DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWGP
SSQPTIPIVGIVAGLAVLAVLAVLGAVMAVVMCRRKSSGGKGGSCSQAAS
SNSAQGSDESLIACKA
 ----+----1----+----2----+----3----+----4----+----5
Hydropathies  
 

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