Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

1422

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P07970 (Created: 1988-08-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_INCMI

Protein Name

Hemagglutinin-esterase-fusion glycoprotein

Gene

Organism Scientific

Influenza C virus (strain C/Mississippi/1980)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus C

Protein Length [aa]

641

Protein Mass [Da]

70610

Features

TypeDescriptionStatusStartEnd
signal peptide         1   1
chain   Hemagglutinin-esterase-fusion glycoprotein chain 1      2   432
chain   Hemagglutinin-esterase-fusion glycoprotein chain 2      433   641
disulfide bond   Interchain (between HEF1 and HEF2 chains)   by similarity   7   569
disulfide bond      by similarity   107   152
disulfide bond      by similarity   127   175
disulfide bond      by similarity   196   238
disulfide bond      by similarity   215   302
disulfide bond      by similarity   223   275
disulfide bond      by similarity   332   338
transmembrane region      potential   617   637
topological domain   Extracellular   potential   1   616
topological domain   Cytoplasmic   potential   638   641
region of interest   Fusion domain-1   by similarity   2   27
region of interest   Esterase domain-1   by similarity   28   138
region of interest   N-acetyl-9-O-acetylneuraminic acid binding   by similarity   138   296
region of interest   Esterase domain-2   by similarity   297   351
region of interest   Fusion domain-2   by similarity   352   637
glycosylation site   N-linked (GlcNAc...)   potential   13   13
glycosylation site   N-linked (GlcNAc...)   potential   48   48
glycosylation site   N-linked (GlcNAc...)   potential   131   131
glycosylation site   N-linked (GlcNAc...)   potential   381   381
active site   Nucleophile   by similarity   58   58
active site   Charge relay system   by similarity   352   352
active site   Charge relay system   by similarity   355   355
non-terminal residue         1   1

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

Sequence

AEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQS
TWIGFGDSRTDKSNPNFPRSADVSVKTANKFRSLTGGSLMLSMFGPPGKV
DYLYQGCGKHKVFYEGVNWSPHAAIDCYRKNWTDIKLNFQKNIYELASQS
HCMSLVNALDKTIPLQATAGVAGNCNNSFLKNPALYTQEVTPPEKCGKEN
LAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCDNYFQVIYDSSG
KVVGGLDNRVSPYTGNTGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERS
YCFDMKEKGLVTAVQSIWGKDRKSDYAVDQACLSTPGCMLIQKQKPYTGE
ADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRCP
LAAKEESIPKIPDGLLIPTSGTDTTVTKPKSRIFGIDDLIIGLLFVAIVE
AGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLND
RITHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWEL
ASEITNRAGDLAVEISPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPPL
DTKIDLQSDPFYWGSSLGLAITTPISLAALVISGIAICRTK

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website