Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

2298

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P20872 (Created: 1991-02-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ENV_HV2ST

Protein Name

Envelope glycoprotein gp160

Gene

env

Organism Scientific

Human immunodeficiency virus type 2 (isolate ST subtype A)

Organism Common

HIV-2

Lineage

Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Lentivirus
          Primate lentivirus group

Protein Length [aa]

859

Protein Mass [Da]

99070

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   24
chain   Envelope glycoprotein gp160      25   859
chain   Surface protein   by similarity   25   505
chain   Transmembrane protein   by similarity   506   859
disulfide bond      by similarity   43   56
disulfide bond      by similarity   100   208
disulfide bond      by similarity   107   199
disulfide bond      by similarity   112   157
disulfide bond      by similarity   221   251
disulfide bond      by similarity   231   243
disulfide bond      by similarity   299   332
disulfide bond      by similarity   384   441
disulfide bond      by similarity   391   414
transmembrane region      potential   674   694
topological domain   Extracellular   potential   25   673
topological domain   Cytoplasmic   potential   695   859
region of interest   V1      112   156
region of interest   V2      157   199
region of interest   V3      299   331
region of interest   V4      391   414
region of interest   V5      457   463
region of interest   Fusion peptide   potential   506   526
region of interest   Immunosuppression   by similarity   569   585
glycosylation site   N-linked (GlcNAc...)   potential   36   36
glycosylation site   N-linked (GlcNAc...)   potential   69   69
glycosylation site   N-linked (GlcNAc...)   potential   78   78
glycosylation site   N-linked (GlcNAc...)   potential   113   113
glycosylation site   N-linked (GlcNAc...)   potential   119   119
glycosylation site   N-linked (GlcNAc...)   potential   131   131
glycosylation site   N-linked (GlcNAc...)   potential   137   137
glycosylation site   N-linked (GlcNAc...)   potential   145   145
glycosylation site   N-linked (GlcNAc...)   potential   160   160
glycosylation site   N-linked (GlcNAc...)   potential   173   173
glycosylation site   N-linked (GlcNAc...)   potential   186   186
glycosylation site   N-linked (GlcNAc...)   potential   200   200
glycosylation site   N-linked (GlcNAc...)   potential   232   232
glycosylation site   N-linked (GlcNAc...)   potential   235   235
glycosylation site   N-linked (GlcNAc...)   potential   242   242
glycosylation site   N-linked (GlcNAc...)   potential   266   266
glycosylation site   N-linked (GlcNAc...)   potential   272   272
glycosylation site   N-linked (GlcNAc...)   potential   283   283
glycosylation site   N-linked (GlcNAc...)   potential   294   294
glycosylation site   N-linked (GlcNAc...)   potential   304   304
glycosylation site   N-linked (GlcNAc...)   potential   359   359
glycosylation site   N-linked (GlcNAc...)   potential   392   392
glycosylation site   N-linked (GlcNAc...)   potential   402   402
glycosylation site   N-linked (GlcNAc...)   potential   405   405
glycosylation site   N-linked (GlcNAc...)   potential   442   442
glycosylation site   N-linked (GlcNAc...)   potential   457   457
glycosylation site   N-linked (GlcNAc...)   potential   460   460
glycosylation site   N-linked (GlcNAc...)   potential   605   605
glycosylation site   N-linked (GlcNAc...)   potential   614   614
glycosylation site   N-linked (GlcNAc...)   potential   630   630
site   Cleavage; by host furin   potential   505   506
compositionally biased region   Poly-Thr      120   129
compositionally biased region   Poly-Gln      543   547
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   767   767
coiled-coil region      potential   535   585
coiled-coil region      potential   622   656

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MCGRNQLFVASLLASACLIYCVQY

Sequence

MCGRNQLFVASLLASACLIYCVQYVTVFYGVPVWRNASIPLFCATKNRDT
WGTIQCLPDNDDYQEIALNVTEAFDAWNNTVTEQAVEDVWSLFETSIKPC
VKLTPLCVAMRCNSTTAKNTTSTPTTTTTANTTIGENSSCIRTDNCTGLG
EEEMVDCQFNMTGLERDKKKLYNETWYSKDVVCESNDTKKEKTCYMNHCN
TSVITESCDKHYWDTMRFRYCAPPGFALLRCNDTNYSGFEPNCSKVVAAT
CTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKFYNLTVHCK
RPGNKTVVPITLMSGLVFHSQPINRRPRQAWCWFKGEWKEAMKEVKLTLA
KHPRYKGTNDTEKIRFIAPGERSDPEVAYMWTNCRGEFLYCNMTWFLNWV
ENRTNQTQHNYVPCHIKQIINTWHKVGKNVYLPPREGQLTCNSTVTSIIA
NIDGGENQTNITFSAEVAELYRLELGDYKLIEVTPIGFAPTPVKRYSSAP
VRNKRGVFVLGFLGFLTTAGAAMGAASLTLSAQSRTLLAGIVQQQQQLLD
VVKRQQEMLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTT
VPWVNDTLTPDWNNMTWQEWEQRIRNLEANISESLEQAQIQQEKNMYELQ
KLNSWDVFGNWFDLTSWIKYIQYGVYIVVGIIVLRIVIYVVQMLSRLRKG
YRPVFSSPPAYFQQIHIHKDREQPAREETEEDVGNSVGDNWWPWPIRYIH
FLIRQLIRLLNRLYNICRDLLSRSFQTLQLISQSLRRALTAVRDWLRFNT
AYLQYGGEWIQEAFRAFARATGETLTNAWRGFWGTLGQIGRGILAVPRRI
RQGAEIALL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website