Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

3286

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q9QSQ7 (Created: 2006-06-27 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ENV_HV1VI

Protein Name

Envelope glycoprotein gp160

Gene

env

Organism Scientific

Human immunodeficiency virus type 1 (isolate VI850 group M subtype F1)

Organism Common

HIV-1

Lineage

Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Lentivirus
          Primate lentivirus group

Protein Length [aa]

832

Protein Mass [Da]

93810

Features

TypeDescriptionStatusStartEnd
signal peptide      by similarity   1   31
chain   Envelope glycoprotein gp160   by similarity   32   832
chain   Surface protein   by similarity   32   487
chain   Transmembrane protein   by similarity   488   832
disulfide bond      by similarity   53   73
disulfide bond      by similarity   118   196
disulfide bond      by similarity   125   187
disulfide bond      by similarity   130   147
disulfide bond      by similarity   209   238
disulfide bond      by similarity   219   230
disulfide bond      by similarity   287   321
disulfide bond      by similarity   368   422
disulfide bond      by similarity   375   395
transmembrane region      potential   661   681
topological domain   Extracellular   potential   32   660
topological domain   Cytoplasmic   potential   682   832
region of interest   V1      130   146
region of interest   V2      147   187
region of interest   V3      287   320
region of interest   V4      375   395
region of interest   V5      438   447
region of interest   Fusion peptide   potential   488   508
region of interest   Immunosuppression   by similarity   552   568
region of interest   Involved in GalCer binding   by similarity   638   643
glycosylation site   N-linked (GlcNAc...)   potential   87   87
glycosylation site   N-linked (GlcNAc...)   potential   129   129
glycosylation site   N-linked (GlcNAc...)   potential   132   132
glycosylation site   N-linked (GlcNAc...)   potential   135   135
glycosylation site   N-linked (GlcNAc...)   potential   146   146
glycosylation site   N-linked (GlcNAc...)   potential   150   150
glycosylation site   N-linked (GlcNAc...)   potential   177   177
glycosylation site   N-linked (GlcNAc...)   potential   178   178
glycosylation site   N-linked (GlcNAc...)   potential   188   188
glycosylation site   N-linked (GlcNAc...)   potential   225   225
glycosylation site   N-linked (GlcNAc...)   potential   232   232
glycosylation site   N-linked (GlcNAc...)   potential   253   253
glycosylation site   N-linked (GlcNAc...)   potential   267   267
glycosylation site   N-linked (GlcNAc...)   potential   280   280
glycosylation site   N-linked (GlcNAc...)   potential   286   286
glycosylation site   N-linked (GlcNAc...)   potential   292   292
glycosylation site   N-linked (GlcNAc...)   potential   322   322
glycosylation site   N-linked (GlcNAc...)   potential   329   329
glycosylation site   N-linked (GlcNAc...)   potential   345   345
glycosylation site   N-linked (GlcNAc...)   potential   352   352
glycosylation site   N-linked (GlcNAc...)   potential   382   382
glycosylation site   N-linked (GlcNAc...)   potential   388   388
glycosylation site   N-linked (GlcNAc...)   potential   419   419
glycosylation site   N-linked (GlcNAc...)   potential   425   425
glycosylation site   N-linked (GlcNAc...)   potential   437   437
glycosylation site   N-linked (GlcNAc...)   potential   587   587
glycosylation site   N-linked (GlcNAc...)   potential   592   592
glycosylation site   N-linked (GlcNAc...)   potential   601   601
glycosylation site   N-linked (GlcNAc...)   potential   613   613
site   Cleavage; by host furin   by similarity   487   488
short sequence motif   YXXL motif; contains endocytosis signal   by similarity   688   691
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   740   740
coiled-coil region      potential   518   568
coiled-coil region      potential   609   643

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MRVRGMQRNWQHLGKWGLLFLGILIICNAAD

Sequence

MRVRGMQRNWQHLGKWGLLFLGILIICNAADNLWVTVYYGVPVWKEATTT
LFCASDAKAYEREAHNVWATHACVPTDPNPQEVFLKNVTENFDMWKNNMV
EQMHTDIISLWDQSLKPCVKLTPLCVTLNCTNATNNSQEKPGAMQNCSFN
MTTEVRDKKLKLSALFYRLDIVPIGNNNSSEYRLINCNTSTITQACPKVS
WDPIPIHYCAPAGYAILKCNDKRFNGTGPCKNVSTVQCTHGIKPVVSTQL
LLNGSLAEEGIVIRSQNISNNAKTIIVHLNESVQINCTRPNNNTRKGIHL
GPGQTFYATGAIIGDIRKAHCNISGTQWNNTLEYVKAELKSHFPNNTAIK
FNQSSGGDLEITMHSFNCRGEFFYCDTSGLFNDTGSNNGTITLPCRIKQI
VNMWQGVGRAMYTSPIAGNITCNSNITGLLLTRDGGNESNIETFRPEGGN
MKDNWRSELYKYKVVEIEPLGVAPTKAKRQVVQREKRAAGLGALFLGFLG
DSREHMGAASITLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIK
QLQARVLAVERYLKDQQLLGIWGCSGKLICTTNVPWNSSWSNKSQEEIWN
NMTWMEWEKEISNYSNIIYKLIEESQNQQEKNEQELLALDKWASLWNWFD
ISNWLWYIKIFIMIVGGLIGLRIVFAVLSIVNRVRKGYSPLSLQTLIPSP
RGPDRPEGIEEGGGEQGKDRSVRLVTGFLALAWDDLRNLCLFSYRHLRDF
ILIAARIVDRGLRRGWEALKYLGNLTRYWSQELKNSAISLFNTTAIVVAE
GTDRIIEVLQRAGRAVLNIPRRIRQGAERALL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website