Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

3288

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

Q1A261 (Created: 2006-09-05 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ENV_SIVMB

Protein Name

Envelope glycoprotein gp160

Gene

env

Organism Scientific

Simian immunodeficiency virus (isolate MB66)

Organism Common

SIV-cpz

Lineage

Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Lentivirus
          Primate lentivirus group

Protein Length [aa]

880

Protein Mass [Da]

99656

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   33
chain   Envelope glycoprotein gp160      34   880
chain   Surface protein   by similarity   34   527
chain   Transmembrane protein   by similarity   528   880
disulfide bond      by similarity   57   77
disulfide bond      by similarity   122   229
disulfide bond      by similarity   129   220
disulfide bond      by similarity   134   174
disulfide bond      by similarity   242   271
disulfide bond      by similarity   252   263
disulfide bond      by similarity   319   353
disulfide bond      by similarity   403   461
disulfide bond      by similarity   410   434
transmembrane region      potential   701   721
topological domain   Extracellular   potential   34   700
topological domain   Cytoplasmic   potential   722   880
region of interest   V1   by similarity   134   173
region of interest   V2   by similarity   174   220
region of interest   V3   by similarity   319   352
region of interest   V4   by similarity   410   434
region of interest   V5   by similarity   480   487
region of interest   Fusion peptide   potential   528   548
region of interest   Immunosuppression   by similarity   593   609
glycosylation site   N-linked (GlcNAc...)   potential   91   91
glycosylation site   N-linked (GlcNAc...)   potential   133   133
glycosylation site   N-linked (GlcNAc...)   potential   145   145
glycosylation site   N-linked (GlcNAc...)   potential   148   148
glycosylation site   N-linked (GlcNAc...)   potential   157   157
glycosylation site   N-linked (GlcNAc...)   potential   163   163
glycosylation site   N-linked (GlcNAc...)   potential   173   173
glycosylation site   N-linked (GlcNAc...)   potential   177   177
glycosylation site   N-linked (GlcNAc...)   potential   221   221
glycosylation site   N-linked (GlcNAc...)   potential   256   256
glycosylation site   N-linked (GlcNAc...)   potential   265   265
glycosylation site   N-linked (GlcNAc...)   potential   286   286
glycosylation site   N-linked (GlcNAc...)   potential   299   299
glycosylation site   N-linked (GlcNAc...)   potential   312   312
glycosylation site   N-linked (GlcNAc...)   potential   318   318
glycosylation site   N-linked (GlcNAc...)   potential   324   324
glycosylation site   N-linked (GlcNAc...)   potential   356   356
glycosylation site   N-linked (GlcNAc...)   potential   372   372
glycosylation site   N-linked (GlcNAc...)   potential   381   381
glycosylation site   N-linked (GlcNAc...)   potential   411   411
glycosylation site   N-linked (GlcNAc...)   potential   417   417
glycosylation site   N-linked (GlcNAc...)   potential   423   423
glycosylation site   N-linked (GlcNAc...)   potential   429   429
glycosylation site   N-linked (GlcNAc...)   potential   464   464
glycosylation site   N-linked (GlcNAc...)   potential   479   479
glycosylation site   N-linked (GlcNAc...)   potential   628   628
glycosylation site   N-linked (GlcNAc...)   potential   633   633
glycosylation site   N-linked (GlcNAc...)   potential   642   642
glycosylation site   N-linked (GlcNAc...)   potential   654   654
site   Cleavage; by host furin   by similarity   527   528
short sequence motif   YXXL motif; contains endocytosis signal   by similarity   729   732
coiled-coil region      potential   559   609
coiled-coil region      potential   650   684

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKAMETQRNCRTLSLKEIILCTLVLGIIGIIKC

Sequence

MKAMETQRNCRTLSLKEIILCTLVLGIIGIIKCEDNMWVTVYYGVPVWRE
ADTTLFCASDAKAQNPEVHNVWASQACVSTNPNPEEIELTNVTEYFNAWE
NNMVEQMHEDIVNLWDQSVKPCVKLIPLCVTLNCSLFKCIKENGNTTNCT
VQISTGNDSTANNITVGTIDMYNCSFNATTELRDRKKQVYSLFYRQDLEP
LEGNKPPEGDKNALYRLYNCNTTAMTQACSKVSLEPIPIHYCAPAGFALL
KCNDKNFTGIGQCKNVSTVHCTHGIRPVVSTQFLLNGTLEEKVTVLDRNV
SNDMDTIIVKLNETVRLNCTRTGNNTIKGIPIGPSQIFYGIETVIGDTRQ
AFCQLNKTVWTNTFKKVRHALNETYKGYLGNETITFGPSTGGDLEVTNLH
LICGGEFFYCNTSILFNTSIIFNETKDDNITIPCRIRQIVRLWQRVGRGI
FLPPIRGTINCISNITGILFAQQKTDRMNKSAMFTPVGGEMRNNWRSELY
KYKVVRIEPLGVAPTKAKRRTVHREKRAAVGLGALFLGFLGAAGSTMGAA
SLTLTVQARQLLSGIVQQQSNLLRAIEAQQHLLQLSVWGIKQLQARVLAV
ERYLKDQQLLGLWGCSGKLICTTSVPWNTTWTNKSYDDIWYNMTWMQWDK
EVSNYTDVIYNLLEKAQTQQENNEKELLELDKWASLWNWFDITSWLWYIK
IFIIIVGGLIGLRIVFALLSIVNRVRQGYSPLSFQTLIPARRDRDRPEEI
EEGGGEPDNVRSIRLVSGFLALAWNDLRDLCLFLYHRLRDLLLIVLRTLE
LVGQTLLKGLRRGREALIHLRGILQYWGQELKTSAISLLDTTAIAVAEGT
DRIIEIAQRFGRGILNIPRRIRQGLERALL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website