Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

3417

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P03443 (Created: 1986-07-21 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_I76A1

Protein Name

Hemagglutinin

Gene

Organism Scientific

Influenza A virus (strain A/Duck/Alberta/28/1976 H4N6)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus A

Protein Length [aa]

564

Protein Mass [Da]

63382

Features

TypeDescriptionStatusStartEnd
signal peptide         1   16
chain   Hemagglutinin HA1 chain      17   342
chain   Hemagglutinin HA2 chain      344   564
disulfide bond   Interchain (between HA1 and HA2 chains)   by similarity   26   480
disulfide bond      by similarity   64   291
disulfide bond      by similarity   76   88
disulfide bond      by similarity   109   151
disulfide bond      by similarity   295   319
disulfide bond      by similarity   487   491
transmembrane region      potential   528   548
topological domain   Extracellular   potential   17   527
topological domain   Cytoplasmic   potential   549   564
glycosylation site   N-linked (GlcNAc...)   potential   18   18
glycosylation site   N-linked (GlcNAc...)   potential   34   34
glycosylation site   N-linked (GlcNAc...)   potential   178   178
glycosylation site   N-linked (GlcNAc...)   potential   310   310
glycosylation site   N-linked (GlcNAc...)   potential   497   497
site   Cleavage; by host   by similarity   343   344
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   553   553
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   560   560
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   563   563

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MLSITILFLLIAEGSS

Sequence

MLSITILFLLIAEGSSQNYTGNPVICLGHHAVSNGTMVKTLTDDQVEVVT
AQELVESQHLPELCPSPLRLVDGQTCDIVNGALGSPGCDHLNGAEWDVFI
ERPTAVDTCYPFDVPDYQSLRSILANNGKFEFIAEEFQWNTVKQNGKSGA
CKRANVNDFFNRLNWLTKSDGDAYPLQNLTKVNNGDYARLYIWGVHHPST
DTEQTNLYKNNPGRVTVSTKTSQTSVVPNIGSRPWVRGQSGRISFYWTIV
EPGDLIVFNTIGNLIAPRGHYKLNSQKKSTILNTAVPIGSCVSKCHTDRG
SISTTKPFQNISRISIRDCPKYVKQGSLKLATGMRNIPEKATRGLFGAIA
GFIENGWQGLIDGWYGFRHQNAEGTGTAADLKSTQAAIDQINGKLNRLIE
KTNEKYHQIEKEFEQVEGRIQDLEKYVEDTKIDLWSYNAEFLVALENQHT
IDVTDSEMNKLFERVRRQLRENAEDKGNGCFEIFHQCDNNCIESIRNGTY
DHDIYRDEAINNRFQIQGVKLTQGYKDIILWISFSISCFLLVALLLAFIL
WACQNGNIRCQICI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website