Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

3419

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P16999 (Created: 1990-08-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_I85A5

Protein Name

Hemagglutinin

Gene

Organism Scientific

Influenza A virus (strain A/Equine/Santiago/1/1985 H3N8)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus A

Protein Length [aa]

565

Protein Mass [Da]

63665

Features

TypeDescriptionStatusStartEnd
signal peptide         1   16
chain   Hemagglutinin HA1 chain      17   343
chain   Hemagglutinin HA2 chain      345   565
disulfide bond   Interchain (between HA1 and HA2 chains)   by similarity   29   481
disulfide bond      by similarity   67   292
disulfide bond      by similarity   79   91
disulfide bond      by similarity   112   154
disulfide bond      by similarity   296   320
disulfide bond      by similarity   488   492
transmembrane region      potential   530   550
topological domain   Extracellular   potential   17   529
topological domain   Cytoplasmic   potential   551   565
glycosylation site   N-linked (GlcNAc...)   potential   23   23
glycosylation site   N-linked (GlcNAc...)   potential   37   37
glycosylation site   N-linked (GlcNAc...)   potential   53   53
glycosylation site   N-linked (GlcNAc...)   potential   78   78
glycosylation site   N-linked (GlcNAc...)   potential   180   180
glycosylation site   N-linked (GlcNAc...)   potential   300   300
glycosylation site   N-linked (GlcNAc...)   potential   498   498
site   Cleavage; by host   by similarity   344   345
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   554   554
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   561   561
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   564   564

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MKTTIILILLTHWVYS

Sequence

MKTTIILILLTHWVYSQNPTSGNNTATLCLGHHAVANGTLVKTITDDQIE
VTNATELVQSISIGKICNNPYRVLDGRNCTLIDAMLGYPHCDVFQYENWD
LFIERSSTFSNCYPYDIPDYASLRSIVASSGTLEFTAEGFTWTGVTQNGR
SGACKRGSADSFFSRLNWLTKSGNSYPTLNVTMPNNNNFDKLYIWGIHHP
SSNNEQTKLYIQESGRVTVSTKRSQQTIIPNIGSRPGIRGQSGRISIYWT
IVKPGDILMVNSNGNLVAPRGYFKMRTGKSSVMRSDAPIDTCVSECITPN
GSIPNDKPFQNVNKVTYGKCPKYIKQNTLKLATGMRNVPEKQIRGIFGAI
AGFIENGWEGMVDGWYGFRYQNSEGTGQAGDLKSTQAAIDQINGKLNRVI
ERTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQH
TIDLTDAEMNKLFEKTRRQLRENAEDMGGGCFKIYHKCDNACIGSIRNGT
YDHYIYRDEALNNRFQIRGVELKSGYKDWILWISFAISCFLICVVLLGFI
MWACQKGNIRCNICI

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website