Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

4289

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P14075 (Created: 1990-01-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ENV_HTL1C

Protein Name

Envelope glycoprotein gp62

Gene

env

Organism Scientific

Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A)

Organism Common

HTLV-1

Lineage

Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Deltaretrovirus

Protein Length [aa]

488

Protein Mass [Da]

53912

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   20
chain   Envelope glycoprotein gp62      21   488
chain   Surface protein   by similarity   21   312
chain   Transmembrane protein   by similarity   313   488
disulfide bond   Alternate   by similarity   225   228
disulfide bond   Interchain (between SU and TM chains, or C-228 with C-401); alternate   by similarity   225   401
disulfide bond      by similarity   393   400
transmembrane region      potential   443   463
topological domain   Extracellular   potential   21   442
topological domain   Cytoplasmic   potential   464   488
region of interest   Fusion peptide   potential   313   333
region of interest   Immunosuppression   by similarity   376   392
glycosylation site   N-linked (GlcNAc...)   potential   140   140
glycosylation site   N-linked (GlcNAc...)   potential   222   222
glycosylation site   N-linked (GlcNAc...)   potential   244   244
glycosylation site   N-linked (GlcNAc...)   potential   272   272
glycosylation site   N-linked (GlcNAc...)   potential   404   404
site   Cleavage; by host furin   by similarity   312   313
short sequence motif   CXXC      225   228
short sequence motif   CX6CC      393   401
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   462   462
coiled-coil region      potential   341   387
coiled-coil region      potential   397   429

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MGKFLATLILFFQFCPLILG

Sequence

MGKFLATLILFFQFCPLILGDYSPSCCTLTVGVSSYHSKPCNPAQPVCSW
TLDLLALSADQALQPPCPNLVSYSSYHATYSLYLFPHWIKKPNRNGGGYY
SASYSDPCSLKCPYLGCQSWTCPYTGAVSSPYWKFQQDVNFTQEVSHLNI
NLHFSKCGFSFSLLVDAPGYDPIWFLNTEPSQLPPTAPPLLSHSNLDHIL
EPSIPWKSKLLTLVQLTLQSTNYTCIVCIDRASLSTWHVLYSPNVSVPSP
SSTPLLYPSLALPAPHLTLPFNWTHCFDPQIQAIVSSPCHNSLILPPFSL
SPVPTLGSRSRRAVPVAVWLVSALAMGAGVAGRITGSMSLASGKSLLHEV
DKDISQLTQAIVKNHKNLLKIAQYAAQNRRGLDLLFWEQGGLCKALQEQC
CFLNITNSHVSILQERPPLENRVLTGWGLNWDLGLSQWAREALQTGITLV
ALLLLVILAGPCILRQLRHLPSRVRYPHYSLINPESSL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website