Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

4291

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P15831 (Created: 1990-04-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

ENV_HV2D2

Protein Name

Envelope glycoprotein gp160

Gene

env

Organism Scientific

Human immunodeficiency virus type 2 (isolate D205 subtype B)

Organism Common

HIV-2

Lineage

Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Lentivirus
          Primate lentivirus group

Protein Length [aa]

859

Protein Mass [Da]

98607

Features

TypeDescriptionStatusStartEnd
signal peptide      potential   1   23
chain   Envelope glycoprotein gp160      24   859
chain   Surface protein   by similarity   24   513
chain   Transmembrane protein   by similarity   514   859
disulfide bond      by similarity   44   57
disulfide bond      by similarity   101   214
disulfide bond      by similarity   108   205
disulfide bond      by similarity   113   164
disulfide bond      by similarity   227   257
disulfide bond      by similarity   237   249
disulfide bond      by similarity   305   338
disulfide bond      by similarity   392   449
disulfide bond      by similarity   399   422
transmembrane region      potential   679   699
topological domain   Extracellular   potential   24   678
topological domain   Cytoplasmic   potential   700   859
region of interest   V1      113   163
region of interest   V2      164   205
region of interest   V3      305   337
region of interest   V4      399   422
region of interest   V5      465   471
region of interest   Fusion peptide   potential   514   534
region of interest   Immunosuppression   by similarity   577   593
glycosylation site   N-linked (GlcNAc...)   potential   37   37
glycosylation site   N-linked (GlcNAc...)   potential   70   70
glycosylation site   N-linked (GlcNAc...)   potential   112   112
glycosylation site   N-linked (GlcNAc...)   potential   122   122
glycosylation site   N-linked (GlcNAc...)   potential   142   142
glycosylation site   N-linked (GlcNAc...)   potential   150   150
glycosylation site   N-linked (GlcNAc...)   potential   165   165
glycosylation site   N-linked (GlcNAc...)   potential   191   191
glycosylation site   N-linked (GlcNAc...)   potential   206   206
glycosylation site   N-linked (GlcNAc...)   potential   238   238
glycosylation site   N-linked (GlcNAc...)   potential   241   241
glycosylation site   N-linked (GlcNAc...)   potential   248   248
glycosylation site   N-linked (GlcNAc...)   potential   272   272
glycosylation site   N-linked (GlcNAc...)   potential   278   278
glycosylation site   N-linked (GlcNAc...)   potential   289   289
glycosylation site   N-linked (GlcNAc...)   potential   300   300
glycosylation site   N-linked (GlcNAc...)   potential   310   310
glycosylation site   N-linked (GlcNAc...)   potential   343   343
glycosylation site   N-linked (GlcNAc...)   potential   367   367
glycosylation site   N-linked (GlcNAc...)   potential   400   400
glycosylation site   N-linked (GlcNAc...)   potential   410   410
glycosylation site   N-linked (GlcNAc...)   potential   413   413
glycosylation site   N-linked (GlcNAc...)   potential   450   450
glycosylation site   N-linked (GlcNAc...)   potential   464   464
glycosylation site   N-linked (GlcNAc...)   potential   468   468
glycosylation site   N-linked (GlcNAc...)   potential   613   613
glycosylation site   N-linked (GlcNAc...)   potential   622   622
glycosylation site   N-linked (GlcNAc...)   potential   638   638
site   Cleavage; by host furin   by similarity   513   514
compositionally biased region   Poly-Thr      126   129
compositionally biased region   Poly-Gln      551   555
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   775   775
coiled-coil region      potential   543   593
coiled-coil region      potential   630   664

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MAYFSSRLPIALLLIGISGFVCK

Sequence

MAYFSSRLPIALLLIGISGFVCKQYVTVFYGIPAWRNATVPLICATTNRD
TWGTVQCLPDNGDYTEIRLNITEAFDAWDNTVTQQAVDDVWRLFETSIKP
CVKLTPLCVAMNCSKTETNPGNASSTTTTKPTTTSRGLKTINETDPCIKN
DSCTGLGEEEIMQCNFSMTGLRRDELKQYKDTWYSEDLECNNTRKYTSRC
YIRTCNTTIIQESCDKHYWDSLRFRYCAPPGFFLLRCNDTNYSGFMPNCS
KVVASSCTRMMETQSSTWFGFNGTRAENRTYIYWHEKDNRTIISLNTYYN
LSIHCKRPGNKTVVPIRTVSGLLFHSQPINKRPRQAWCWFKGNWTEAIKE
VKRTIIKHPRYKGGAKNITSVKLVSEHGKGSDPETTYMWTNCRGEFLYCN
MTWFLNWVENKTNTTRRNYAPCHIRQIINTWHKVGKNIYLPPREGELSCN
STVTSLIANINSDNSTTNISVSAEVSELYRLELGDYKLVEITPIGFAPTD
VRRYSSVKPRNKRGVMVLGFLGFLAMAGSAMGATSLTLSAQSRTLLAGIV
QQQQQPVDVVKRQQELLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCA
FRQVCHTTVPWPNETLTPNWNNMTWQQWEKQVHFLDANITALLEEAQIQQ
EKNMYELQKINSWDVFGNWFDLTSWIKYIHLGLYIVAGLVVLRIVVYIVQ
MLARLRKGYRPVFSSPPSYTQQIPIRKDRGQPANEETEEGGGNDGDYRSW
PWQIEYIHFLLRQLRNLLIWLYNGCRTLLLKTFQILHQISTNLQPLRLPV
AYLQYGISWFQEALRAAARATGETLASAGETLWEALRRAARAIIAIPRRI
RQGLELTLL

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website