Signal Peptide Database - Viruses

 Entry Details
ID   4293
Source Database   UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number   P03379    (Created: 1986-07-21 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name   ENV_VILV
Protein Name   Envelope glycoprotein gp160
Gene   env
Organism Scientific   Maedi visna virus (strain 1514)
Organism Common   MVV
Lineage   Viruses
  Retro-transcribing viruses
    Retroviridae
      Orthoretrovirinae
        Lentivirus
          Ovine/caprine lentivirus group
Protein Length [aa]   982
Protein Mass [Da]   113978
Features  
TypeDescriptionStatusStartEnd
signal peptide      potential   1   106
chain   Envelope glycoprotein gp160      107   982
chain   Surface protein   by similarity   107   656
chain   Transmembrane protein   by similarity   657   982
transmembrane region      potential   832   852
topological domain   Extracellular   potential   107   831
topological domain   Cytoplasmic   potential   853   982
region of interest   Fusion peptide      657   677
region of interest   Immunosuppression   by similarity   723   738
glycosylation site   N-linked (GlcNAc...)   potential   140   140
glycosylation site   N-linked (GlcNAc...)   potential   161   161
glycosylation site   N-linked (GlcNAc...)   potential   206   206
glycosylation site   N-linked (GlcNAc...)   potential   258   258
glycosylation site   N-linked (GlcNAc...)   potential   298   298
glycosylation site   N-linked (GlcNAc...)   potential   364   364
glycosylation site   N-linked (GlcNAc...)   potential   370   370
glycosylation site   N-linked (GlcNAc...)   potential   381   381
glycosylation site   N-linked (GlcNAc...)   potential   387   387
glycosylation site   N-linked (GlcNAc...)   potential   403   403
glycosylation site   N-linked (GlcNAc...)   potential   414   414
glycosylation site   N-linked (GlcNAc...)   potential   435   435
glycosylation site   N-linked (GlcNAc...)   potential   439   439
glycosylation site   N-linked (GlcNAc...)   potential   470   470
glycosylation site   N-linked (GlcNAc...)   potential   475   475
glycosylation site   N-linked (GlcNAc...)   potential   481   481
glycosylation site   N-linked (GlcNAc...)   potential   491   491
glycosylation site   N-linked (GlcNAc...)   potential   501   501
glycosylation site   N-linked (GlcNAc...)   potential   515   515
glycosylation site   N-linked (GlcNAc...)   potential   527   527
glycosylation site   N-linked (GlcNAc...)   potential   537   537
glycosylation site   N-linked (GlcNAc...)   potential   542   542
glycosylation site   N-linked (GlcNAc...)   potential   543   543
glycosylation site   N-linked (GlcNAc...)   potential   568   568
glycosylation site   N-linked (GlcNAc...)   potential   697   697
glycosylation site   N-linked (GlcNAc...)   potential   764   764
glycosylation site   N-linked (GlcNAc...)   potential   771   771
glycosylation site   N-linked (GlcNAc...)   potential   787   787
glycosylation site   N-linked (GlcNAc...)   potential   821   821
site   Cleavage; by host   by similarity   656   657
compositionally biased region   Poly-Lys      958   961
lipid moiety-binding region   S-palmitoyl cysteine; by host   by similarity   855   855
coiled-coil region      potential   689   738
coiled-coil region      potential   779   814
SP Length   106
 ----+----1----+----2----+----3----+----4----+----5
Signal Peptide MASKESKPSRTTWRDMEPPLRETWNQVLQELVKRQQQEEEEQQGLVSGKK
KSWVSIDLLGTEGKDIKKVNIWEPCEKWFAQVVWGVLWVLQIVLWGCLMW
EVRKGN
Sequence MASKESKPSRTTWRDMEPPLRETWNQVLQELVKRQQQEEEEQQGLVSGKK
KSWVSIDLLGTEGKDIKKVNIWEPCEKWFAQVVWGVLWVLQIVLWGCLMW
EVRKGN
QCQAEEVIALVSDPGGFQRVQHVETVPVTCVTKNFTQWGCQPEG
AYPDPELEYR
NISREILEEVYKQDWPWNTYHWPLWQMENMRQWMKENEKE
YKERT
NKTKEDIDDLVAGRIRGRFCVPYPYALLRCEEWCWYPESINQETG
HAEKIKI
NCTKAKAVSCTEKMPLAAVQRVYWEKEDEESMKFLNIKACNIS
LRCQDEGKSPGGCVQGYPIPKGAEIIPEAMKYLRGKKSRYGGIKDKNGEL
KLPLSVRVWVRMA
NLSGWVNGTPPYWSARINGSTGINGTRWYGVGTLHHL
GY
NISSNPEGGICNFTGELWIGGDRFPYYYKPSWNCSQNWTGHPVWHVFR
YLDMTEHMTSRCIQRPKRH
NITVGNGTITGNCSVTNWDGCNCTRSGNHLY
NSTSGGLLVIICRQNSTITGIMGTNTNWTTMWNIYQNCSRCNNSSLDRTG
SGTLGTVNNLKCSLPHR
NESNKWTCKSQRDSYIAGRDFWGKVKAKYSCES
NLGGLDSMMHQQMLLQRYQVIRVRAYTYGVVEMPQSYMEERGENRRSRRN
LQRKK
RGIGLVIVLAIMAIIAAAGAGLGVANAVQQSYTRTAVQSLANATA
AQQEVLEASYAMVQHIAKGIRILEARVARVEALVDMMV
YQELDCWHYQHY
CVTSTRSEVANYV
NWTRFKDNCTWQQWEEEIEQHEGNLSLLLREAALQVH
IAQRDARRIPDAWK
AIQEAFNWSSWFSWLKYIPWIIMGIVGLMCFRILMC
VI
SMCLQAYKQVKQIRYTQVTVVIEAPVELEEKQKRNGDGTNGCASLEHE
RRTSHRSFIQIWRATWWAWKTSPWRHNWRTMPYITLLPILVIWQWMEENG
WNGENQH
KKKKERVDCQDREQMPTLENDYVEL
Original MASKESKPSRTTWRDMEPPLRETWNQVLQELVKRQQQEEEEQQGLVSGKK
KSWVSIDLLGTEGKDIKKVNIWEPCEKWFAQVVWGVLWVLQIVLWGCLMW
EVRKGNQCQAEEVIALVSDPGGFQRVQHVETVPVTCVTKNFTQWGCQPEG
AYPDPELEYRNISREILEEVYKQDWPWNTYHWPLWQMENMRQWMKENEKE
YKERTNKTKEDIDDLVAGRIRGRFCVPYPYALLRCEEWCWYPESINQETG
HAEKIKINCTKAKAVSCTEKMPLAAVQRVYWEKEDEESMKFLNIKACNIS
LRCQDEGKSPGGCVQGYPIPKGAEIIPEAMKYLRGKKSRYGGIKDKNGEL
KLPLSVRVWVRMANLSGWVNGTPPYWSARINGSTGINGTRWYGVGTLHHL
GYNISSNPEGGICNFTGELWIGGDRFPYYYKPSWNCSQNWTGHPVWHVFR
YLDMTEHMTSRCIQRPKRHNITVGNGTITGNCSVTNWDGCNCTRSGNHLY
NSTSGGLLVIICRQNSTITGIMGTNTNWTTMWNIYQNCSRCNNSSLDRTG
SGTLGTVNNLKCSLPHRNESNKWTCKSQRDSYIAGRDFWGKVKAKYSCES
NLGGLDSMMHQQMLLQRYQVIRVRAYTYGVVEMPQSYMEERGENRRSRRN
LQRKKRGIGLVIVLAIMAIIAAAGAGLGVANAVQQSYTRTAVQSLANATA
AQQEVLEASYAMVQHIAKGIRILEARVARVEALVDMMVYQELDCWHYQHY
CVTSTRSEVANYVNWTRFKDNCTWQQWEEEIEQHEGNLSLLLREAALQVH
IAQRDARRIPDAWKAIQEAFNWSSWFSWLKYIPWIIMGIVGLMCFRILMC
VISMCLQAYKQVKQIRYTQVTVVIEAPVELEEKQKRNGDGTNGCASLEHE
RRTSHRSFIQIWRATWWAWKTSPWRHNWRTMPYITLLPILVIWQWMEENG
WNGENQHKKKKERVDCQDREQMPTLENDYVEL
 ----+----1----+----2----+----3----+----4----+----5
Hydropathies  
 

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