Signal Peptide Database

Signal Peptide Database - Viruses

Entry Details

4424

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P07974 (Created: 1988-08-01 Updated: 2008-11-25)

UniProtKB/Swiss-Prot Entry Name

HEMA_INCTA

Protein Name

Hemagglutinin-esterase-fusion glycoprotein

Gene

Organism Scientific

Influenza C virus (strain C/Taylor/1233/1947)

Organism Common

Lineage

Viruses
  ssRNA negative-strand viruses
    Orthomyxoviridae
      Influenzavirus C

Protein Length [aa]

642

Protein Mass [Da]

70762

Features

TypeDescriptionStatusStartEnd
signal peptide         1   1
chain   Hemagglutinin-esterase-fusion glycoprotein chain 1      2   433
chain   Hemagglutinin-esterase-fusion glycoprotein chain 2      434   642
disulfide bond   Interchain (between HEF1 and HEF2 chains)   by similarity   7   570
disulfide bond      by similarity   107   152
disulfide bond      by similarity   127   175
disulfide bond      by similarity   197   239
disulfide bond      by similarity   216   303
disulfide bond      by similarity   224   276
transmembrane region      potential   618   638
topological domain   Extracellular   potential   1   617
topological domain   Cytoplasmic   potential   639   642
region of interest   Fusion domain-1   by similarity   2   27
region of interest   Esterase domain-1   by similarity   28   138
region of interest   N-acetyl-9-O-acetylneuraminic acid binding   by similarity   138   297
region of interest   Esterase domain-2   by similarity   298   352
region of interest   Fusion domain-2   by similarity   353   638
glycosylation site   N-linked (GlcNAc...)   potential   13   13
glycosylation site   N-linked (GlcNAc...)   potential   48   48
glycosylation site   N-linked (GlcNAc...)   potential   131   131
glycosylation site   N-linked (GlcNAc...)   potential   382   382
active site   Nucleophile   by similarity   58   58
active site   Charge relay system   by similarity   353   353
active site   Charge relay system   by similarity   356   356
non-terminal residue         1   1

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

Sequence

AEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQS
TWIGFGDSRTDKSNSAFPRSADVSEKTADKFRSLSGGSLMLSMFGPPGKV
DYLYQGCGKHKVFYEGVNWSPHAAINCYRKNWTDIKLNFQKNIYELASQS
HCMSLVNALDKTIPLQVTAGVAKNCNNSFLKNPALYTQEVNPSKEICGKE
NLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCDNYFQVIYDSS
GKVVGGLDNRVSPYTGNTGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPER
SYCFDMKEKGLVTAVQSVWGKGRESDHAVDQAYLSTPGCMLIQKQKPYIG
EADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRC
PLAAKEESIPKIPDGLLIPTSGTDTIVTKPKSRIFGIDDLIIGLLFVAIV
EAGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLN
DRITHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWE
LASEITNRAGDLAVEVSPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPP
LDTKIDLQSDPFYWGSSLGLAITTPISLAALVISGIAICRTK

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website