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Signal Peptide Database - Viruses
Entry Details
ID
5144
Source Database
UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot Accession Number
P33426 (Created: 1994-02-01 Updated: 2008-11-25)
UniProtKB/Swiss-Prot Entry Name
CAPSD_HEVPA
Protein Name
Capsid protein
Gene
ORF2
Organism Scientific
Hepatitis E virus genotype 1 (isolate Human/Pakistan/Sar-55)
Organism Common
HEV-1
Lineage
Viruses
ssRNA positive-strand viruses, no DNA stage
Hepeviridae
Hepevirus
Protein Length [aa]
660
Protein Mass [Da]
70980
Features
Type
Description
Status
Start
End
signal peptide
potential
1
19
chain
Capsid protein
20
660
region of interest
particle formation
by similarity
368
394
region of interest
Oligomerization
by similarity
585
610
compositionally biased region
Arg/Gly-rich
27
45
compositionally biased region
Poly-Thr
215
220
mutagenesis site
Complete loss of infectivity. Inhibition of capsid assembly
0
0
mutagenesis site
Complete loss of infectivity. Inhibition of capsid assembly
0
0
mutagenesis site
Complete loss of infectivity
0
0
mutagenesis site
Complete loss of infectivity. Loss of dimerization
0
0
SP Length
19
----+----1----+----2----+----3----+----4----+----5
Signal Peptide
MRPRPILLLLLMFLPMLPA
Sequence
MRPRPILLLLLMFLPMLPA
PPPGQPS
GRRRGRRSGGSGGGFWGDR
VDSQP
FAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAAASRR
RPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATG
TNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVARATIRYRPLVPN
AVGGYAISISFWPQ
TTTTPT
SVDMNSITSTDVRILVQPGIASELVIPSER
LHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLL
DFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFM
KDLYFTSTNGVGEIGRG
IALTLFNLADTLLGGLPTELISSAGGQ
LFYSRP
VVSANGEPTVKLYTSVENAQQDKGIAIPHDIDLGESRVVIQDYDNQHEQD
RPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTL
VNVATGAQAVARSLDWTKVTLDGRPLSTIQQYSKTFFVLPLRGKLSFWEA
GTTKAGYPYNYNTTASDQLLVENAAGHRVAISTY
TTSLGAGPVSISAVAV
LAPHSVLALL
EDTMDYPARAHTFDDFCPECRPLGLQGCAFQSTVAELQRL
KMKVGKTREL
Original
MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRVDSQP
FAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAAASRR
RPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATG
TNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVARATIRYRPLVPN
AVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASELVIPSER
LHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLL
DFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFM
KDLYFTSTNGVGEIGRGIALTLFNLADTLLGGLPTELISSAGGQLFYSRP
VVSANGEPTVKLYTSVENAQQDKGIAIPHDIDLGESRVVIQDYDNQHEQD
RPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTL
VNVATGAQAVARSLDWTKVTLDGRPLSTIQQYSKTFFVLPLRGKLSFWEA
GTTKAGYPYNYNTTASDQLLVENAAGHRVAISTYTTSLGAGPVSISAVAV
LAPHSVLALLEDTMDYPARAHTFDDFCPECRPLGLQGCAFQSTVAELQRL
KMKVGKTREL
----+----1----+----2----+----3----+----4----+----5
Hydropathies
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Dr. Katja Kapp
, Kassel &
thpr.net e. K.
, Dresden, Germany, last update 2010-06-11
